SCHEMBL16704555

SCHEMBL16704555

CNC(=O)c1ccc(C(=O)O)c2c(C(=O)Nc3ccc(Oc4ccc(C)cc4)cc3)ccc(OC=O)c12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PNLIP P16233 2/20 0.46
▸ MAPK1 P28482 2/20 0.45
▸ GFER P55789 1/20 0.45
▸ MMP13 P45452 1/20 0.42
▸ ALDH1A1 P00352 3/20 0.42
▸ POLB P06746 3/20 0.42
▸ GAA P10253 2/20 0.42
▸ CRHBP P24387 1/20 0.42
▸ FNTA P49354 1/20 0.42
▸ FNTB P49356 1/20 0.42
▸ CRHR2 Q13324 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ BRAF P15056 3/20 0.41
▸ HDAC1 Q13547 3/20 0.41
▸ HDAC3 O15379 2/20 0.41
▸ HDAC4 P56524 2/20 0.41
▸ HDAC7 Q8WUI4 2/20 0.41
▸ HDAC2 Q92769 2/20 0.41
▸ HDAC10 Q969S8 2/20 0.41
▸ HDAC11 Q96DB2 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16704554 1.00 PNLIP (0.46) PNLIPMAPK1GFERMMP13ALDH1A1
SCHEMBL12894458 0.85 MAPK1 (0.47) PNLIPMAPK1GFERMMP13ALDH1A1
SCHEMBL12555547 0.84 MAPK1 (0.48) PNLIPMAPK1GFERMMP13ALDH1A1
SCHEMBL12894460 0.79 NR1H4 (0.44) MAPK1GFERPOLBGAAL3MBTL1
SCHEMBL12153246 0.79 MAPK1 (0.62) PNLIPMAPK1GFERMMP13ALDH1A1
SCHEMBL12130852 0.78 MAPK1 (0.58) PNLIPMAPK1GFERMMP13ALDH1A1
SCHEMBL9885132 0.78 MAPK1 (0.58) PNLIPMAPK1GFERMMP13ALDH1A1
SCHEMBL12786217 0.78 KMT2A (0.45) PNLIPMAPK1GFERALDH1A1POLB
SCHEMBL12894480 0.78 KMT2A (0.45) PNLIPMAPK1GFERALDH1A1POLB
SCHEMBL15294833 0.77 MAPK1 (0.63) PNLIPMAPK1GFERMMP13ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150277247-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2015-10-01 — — US disclosed
US-20150277246-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2015-10-01 — — US disclosed
US-9069267-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-06-30 — — US disclosed
US-9063505-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-06-23 — — US disclosed
US-9029054-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-05-12 — — US disclosed
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