Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670328 | 0.85 | BRD4 (0.33) | — | |
| SCHEMBL1670517 | 0.84 | KDM1A (0.33) | ESR1ESR2TTRMIFERN1 | |
| SCHEMBL1671024 | 0.83 | TTR (0.34) | ESR1ESR2TTRMIFERN1 | |
| SCHEMBL1670943 | 0.74 | BRD4 (0.35) | — | |
| SCHEMBL12800991 | 0.73 | BRD4 (0.32) | — | |
| SCHEMBL1672792 | 0.72 | ERN1 (0.38) | ERN1HDAC4 | |
| SCHEMBL1682414 | 0.72 | ERN1 (0.38) | ESR1ESR2ERN1HDAC4 | |
| SCHEMBL1671035 | 0.71 | BRD4 (0.33) | ERN1 | |
| SCHEMBL1670276 | 0.70 | BRD4 (0.35) | TTRERN1 | |
| SCHEMBL1672988 | 0.70 | ERN1 (0.40) | ESR1ESR2ERN1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |