Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670276 | 0.86 | BRD4 (0.35) | TTRERN1 | |
| SCHEMBL1670515 | 0.83 | ESR1 (0.33) | TTRMIFESR1ESR2ERN1 | |
| SCHEMBL1671022 | 0.82 | KDM1A (0.35) | TTRARTNIKMIFESR1 | |
| SCHEMBL1671019 | 0.82 | KDM1A (0.35) | TTRARTNIKMIFESR1 | |
| SCHEMBL1670808 | 0.82 | TTR (0.34) | TTRARESR1ESR2 | |
| SCHEMBL1671187 | 0.76 | ERN1 (0.34) | TTRARTNIKMIFESR1 | |
| SCHEMBL1671189 | 0.76 | ERN1 (0.34) | TTRARTNIKMIFESR1 | |
| SCHEMBL1672792 | 0.73 | ERN1 (0.38) | ERN1 | |
| SCHEMBL1682414 | 0.73 | ERN1 (0.38) | ESR1ESR2ERN1 | |
| SCHEMBL1672988 | 0.71 | ERN1 (0.40) | ESR1ESR2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |