Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 9/20 | 0.35 |
| ▸ | BRD2 | P25440 | 2/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.34 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672810 | 0.85 | BRD4 (0.40) | ERN1BRD4BRD2MLYCDHDAC4 | |
| SCHEMBL1670490 | 0.83 | BRD4 (0.35) | ERN1BRD4BCL2L1BAK1NSD3 | |
| SCHEMBL1672865 | 0.82 | BRD4 (0.37) | BRD4BRD2MLYCDHDAC6 | |
| SCHEMBL1682414 | 0.82 | ERN1 (0.38) | ERN1BRD4BRD2BRD3MLYCD | |
| SCHEMBL1672789 | 0.82 | ERN1 (0.38) | ERN1BRD4BRD2BRD3MLYCD | |
| SCHEMBL1672787 | 0.82 | ERN1 (0.38) | ERN1BRD4BRD2BRD3MLYCD | |
| SCHEMBL1672988 | 0.80 | ERN1 (0.40) | ERN1BRD4BRD2BRD3MLYCD | |
| SCHEMBL21141696 | 0.75 | ERN1 (0.35) | ERN1BRD4BRD2BRD3HDAC4 | |
| SCHEMBL1672899 | 0.74 | ERN1 (0.38) | ERN1BRD4MLYCDHDAC4HDAC6 | |
| SCHEMBL1671024 | 0.73 | TTR (0.34) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |