Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014878 | 1.00 | KDM4E (0.35) | KDM4ELMNAALDH1A1MEN1HTT | |
| SCHEMBL16704800 | 1.00 | KDM4E (0.35) | KDM4ELMNAALDH1A1MEN1HTT | |
| SCHEMBL2020308 | 0.83 | — | — | |
| SCHEMBL9317589 | 0.81 | KDM4E (0.38) | KDM4ELMNAALDH1A1EPHX2TDP1 | |
| SCHEMBL21594539 | 0.79 | KDM4E (0.36) | KDM4ELMNAALDH1A1MEN1HTT | |
| SCHEMBL21215002 | 0.77 | KDM4E (0.35) | KDM4ELMNAALDH1A1EPHX2TDP1 | |
| SCHEMBL4545263 | 0.77 | KDM4E (0.39) | KDM4ELMNAALDH1A1EPHX2TDP1 | |
| SCHEMBL2458229 | 0.77 | KDM4E (0.35) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2016534 | 0.76 | KDM4E (0.34) | KDM4ELMNAALDH1A1EPHX2PKM | |
| SCHEMBL2016537 | 0.76 | KDM4E (0.38) | KDM4ELMNAALDH1A1EPHX2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029457-B2 | Silica-supported oligomeric hybrid materials | THE UNIVERSITY OF KANSAS (US) | 2015-05-12 | — | — | US | disclosed |