SCHEMBL16705173

SCHEMBL16705173

CNC(=O)Nc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.71
TIMP3 P35625 1/20 0.58
ALDH1A1 P00352 1/20 0.58
PTPN7 P35236 1/20 0.50
BDKRB1 P46663 1/20 0.50
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
MMP14 P50281 1/20 0.48
CA12 O43570 5/20 0.47
CA1 P00915 5/20 0.47
CA2 P00918 5/20 0.47
CA9 Q16790 5/20 0.47
TP53 P04637 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA13 Q8N1Q1 1/20 0.47
CA14 Q9ULX7 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12049668 0.85 KMT2A (0.71) KMT2AALDH1A1
SCHEMBL10155599 0.83 ALDH1A1 (0.78) KMT2AALDH1A1TP53POLB
SCHEMBL10155593 0.83 KMT2A (0.69) KMT2AALDH1A1BDKRB1MMP2MMP9
SCHEMBL4969968 0.83 KMT2A (0.69) KMT2AALDH1A1PTPN7BDKRB1MMP2
SCHEMBL6252334 0.83 KMT2A (1.00) KMT2AALDH1A1PTPN7CA12CA1
SCHEMBL3460960 0.81 CA12 (0.71) KMT2ATIMP3ALDH1A1CA12CA1
SCHEMBL9651525 0.81 TIMP3 (0.58) KMT2ATIMP3ALDH1A1PTPN7CA12
SCHEMBL16705174 0.81 KMT2A (0.51) KMT2ATIMP3ALDH1A1BDKRB1CA12
SCHEMBL13714615 0.80 DHODH (0.57) KMT2ATIMP3PTPN7MMP2CA12
SCHEMBL11773344 0.80 KMT2A (0.65) KMT2AALDH1A1BDKRB1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9029492-B2 Superconducting electrolytic hybrid material, and preparation method and uses thereof CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2015-05-12 US disclosed