Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9898484 | 0.92 | PRKDC (0.31) | PRKDC | |
| SCHEMBL31337445 | 0.89 | PTPN1 (0.34) | PRKDCAKT1KDM4EALDH1A1TP53 | |
| SCHEMBL9928450 | 0.89 | PRKDC (0.30) | PRKDC | |
| SCHEMBL16705200 | 0.89 | PDK2 (0.31) | — | |
| SCHEMBL18102198 | 0.89 | PRKDC (0.36) | PRKDCAKT1KDM4EALDH1A1TP53 | |
| SCHEMBL9926879 | 0.87 | PRKDC (0.34) | PRKDCAKT1KDM4EALDH1A1TDP1 | |
| SCHEMBL9898614 | 0.87 | ALDH1A1 (0.35) | PRKDCKDM4EALDH1A1TP53TSHR | |
| SCHEMBL25607195 | 0.87 | PRKDC (0.36) | PRKDCAKT1KDM4EALDH1A1TP53 | |
| SCHEMBL9928399 | 0.86 | ALDH1A1 (0.37) | PRKDCAKT1KDM4EALDH1A1TP53 | |
| SCHEMBL25607198 | 0.86 | ALDH1A1 (0.35) | PRKDCAKT1KDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9028728-B2 | Photochromic materials that include indeno-fused naphthopyrans | TRANSITIONS OPTICAL, INC. (US) | 2015-05-12 | — | — | US | disclosed |