Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 3/20 | 0.54 |
| ▸ | CTSV | O60911 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12518059 | 0.88 | BACE1 (0.61) | BACE1CTSBCTSVCTSLCTSS | |
| SCHEMBL12463981 | 0.82 | MMP9 (0.60) | BACE1CTSBCTSVCTSLCTSS | |
| SCHEMBL16571252 | 0.80 | BACE1 (0.62) | BACE1CTSBCTSVCTSLCTSS | |
| SCHEMBL8017638 | 0.80 | CCR3 (0.58) | BACE1CTSBCTSVCTSLCTSS | |
| SCHEMBL8010564 | 0.79 | CCR3 (0.62) | BACE1CTSBCTSVCTSLCTSS | |
| SCHEMBL9716712 | 0.79 | ELANE (0.64) | BACE1CTSBCTSVCTSLCTSS | |
| SCHEMBL10658026 | 0.79 | ELANE (0.64) | BACE1CTSBCTSVCTSLCTSS | |
| SCHEMBL9830992 | 0.79 | MEN1 (0.58) | BACE1CTSBCTSVCTSLCTSS | |
| SCHEMBL9830982 | 0.79 | MEN1 (0.58) | BACE1CTSBCTSVCTSLCTSS | |
| SCHEMBL8008852 | 0.79 | CCR3 (0.55) | BACE1CTSBCTSVCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526116-B1 | PYRUVAMIDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN | ST GEORGES HOSP MEDICAL SCHOOL (GB) | 2015-05-13 | — | — | EP | disclosed |