Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16705683 | 0.88 | SIGMAR1 (0.44) | NOS1NOS3SIGMAR1HTR2AKCNH2 | |
| SCHEMBL16705682 | 0.87 | KCNJ1 (0.48) | SIGMAR1KCNH2 | |
| SCHEMBL31186159 | 0.81 | BCHE (0.53) | BCHEACHEPARP1CHKAKDM4E | |
| SCHEMBL16705656 | 0.81 | BCHE (0.44) | BCHEACHEPARP1CHKAKDM4E | |
| SCHEMBL16718704 | 0.81 | BCHE (0.39) | BCHEACHEPARP1CHKAKDM4E | |
| SCHEMBL18121367 | 0.79 | CXCR4 (0.52) | BCHEACHEPARP1CHKAKDM4E | |
| SCHEMBL465875 | 0.79 | BCHE (0.53) | BCHEACHEPARP1KDM4E | |
| SCHEMBL16728791 | 0.77 | BCHE (0.44) | BCHEACHEPARP1CHKAKDM4E | |
| SCHEMBL3320134 | 0.77 | BCHE (0.53) | BCHEACHEPARP1CHKAKDM4E | |
| SCHEMBL31721289 | 0.77 | BCHE (0.53) | BCHEACHEPARP1CHKAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10434199-B2 | Picolinate cross-bridged cyclams, chelates with metallic cations and use thereof | UNIVERSITÉ DE BRETAGNE OCCIDENTALE (FR) | 2019-10-08 | — | — | US | disclosed |
| EP-3068787-B1 | PICOLINATE CROSS-BRIDGED CYCLAMS, CHELATES WITH METALLIC CATIONS AND USE THEREOF | UNIVERSITÉ DE BRETAGNE OCCIDENTALE (FR) | 2017-11-01 | — | — | EP | disclosed |
| US-20160287733-A1 | PICOLINATE CROSS-BRIDGED CYCLAMS, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-10-06 | — | — | US | disclosed |
| US-20160287733-A1 | PICOLINATE CROSS-BRIDGED CYCLAMS, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-10-06 | — | — | US | disclosed |
| EP-2871186-B1 | Picolinate cross-bridged cyclams, chelates with metallic cations and use thereof | UNIVERSITÉ DE BRETAGNE OCCIDENTALE (FR) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015071334-A1 | PICOLINATE CROSS-BRIDGED CYCLAMS, CHELATES WITH METALLIC CATIONS AND USE THEREOF | UNIVERSITÉ DE BRETAGNE OCCIDENTALE (FR) | 2015-05-21 | — | — | WO | disclosed |
| EP-2871186-A1 | Picolinate cross-bridged cyclams, chelates with metallic cations and use thereof | Université de Bretagne Occidentale (FR) | 2015-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10434199-B2 | Picolinate cross-bridged cyclams, chelates with metallic cations and use thereof | SLC39A14, SLC67A1, SLC39A3 | BCHE 4215/4885ACHE 2031/4885NOS1 2938/4885 |
| US-20160287733-A1 | PICOLINATE CROSS-BRIDGED CYCLAMS, CHELATES WITH METALLIC CATIONS AND USE THEREOF | SLC39A14, SLC67A1, SLC39A3 | BCHE 4215/4885ACHE 2031/4885NOS1 2938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.