SCHEMBL16705960

SCHEMBL16705960

CC[C@H](OC)[C@@H](C)[C@@H]1C[C@@H]1[C@@H](O)[C@H](C)/C=C/C=C(\C)[C@H]1OC(=O)C[C@H](O)CC[C@@](C)(O)[C@@H](OC(C)=O)/C=C/[C@@H]1C

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SF3B3 Q15393 10/20 0.50
HMGCR P04035 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15296993 1.00 SF3B3 (0.50) SF3B3HMGCR
SCHEMBL16705979 1.00 SF3B3 (0.50) SF3B3HMGCR
SCHEMBL15296992 1.00 SF3B3 (0.50) SF3B3HMGCR
SCHEMBL16705940 0.91 SF3B3 (0.46) SF3B3
SCHEMBL16705950 0.91 SF3B3 (0.46) SF3B3
SCHEMBL16705945 0.91 SF3B3 (0.46) SF3B3
SCHEMBL16705967 0.91 SF3B3 (0.46) SF3B3
SCHEMBL3550393 0.91 SF3B3 (0.55) SF3B3
SCHEMBL12298672 0.91 SF3B3 (0.55) SF3B3
SCHEMBL15297008 0.91 SF3B3 (0.55) SF3B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9604973-B2 Anti-cancer polyketide compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-03-28 US disclosed
US-9604973-B2 Anti-cancer polyketide compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-03-28 US disclosed
US-20150133535-A1 ANTI-CANCER POLYKETIDE COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2015-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150133535-A1 ANTI-CANCER POLYKETIDE COMPOUNDS SRPK3, HNRNPK, SRPK1 SF3B3 192/4885HMGCR 1797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.