SCHEMBL3550393

SCHEMBL3550393

CCC(OC)C(C)C1OC1C(O)C(C)/C=C/C=C(\C)C1OC(=O)CC(O)CCC(C)(O)C(OC(C)=O)/C=C/C1C

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SF3B3 Q15393 10/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14396018 1.00 SF3B3 (0.55) SF3B3
SCHEMBL16705942 1.00 SF3B3 (0.55) SF3B3
SCHEMBL15297008 1.00 SF3B3 (0.55) SF3B3
SCHEMBL12298672 1.00 SF3B3 (0.55) SF3B3
SCHEMBL15297013 1.00 SF3B3 (0.55) SF3B3
SCHEMBL15297009 1.00 SF3B3 (0.55) SF3B3
SCHEMBL14397315 1.00 SF3B3 (0.55) SF3B3
SCHEMBL14396324 0.95 SF3B3 (0.55) SF3B3
SCHEMBL14397399 0.95 SF3B3 (0.51) SF3B3
SCHEMBL14396935 0.95 SF3B3 (0.51) SF3B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024119113-A1 COMPOSITIONS AND METHODS FOR SPLICEOSOME-TARGETED THERAPIES INSTITUTE CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER (US) 2024-06-06 WO claimed
US-20240148688-A1 METHODS FOR TREATING AND AMELIORATING CANCER UNIV CALIFORNIA (US) 2024-05-09 US claimed
EP-4361136-A1 COMPOUND FOR THE TREATMENT OF GLIOBLASTOMA Universidad De Córdoba (ES) 2024-05-01 EP claimed
EP-4284519-A1 METHODS FOR TREATING AND AMELIORATING CANCER The Regents of the University of California (US) 2023-12-06 EP claimed
CN-116829142-A Methods for treating and ameliorating cancer 加利福尼亚大学董事会 2023-09-29 CN claimed
US-20230190707-A1 COMPOSITIONS AND METHODS FOR ENHANCING CANCER IMMUNOTHERAPY FRED HUTCHINSON CANCER CENTER (US) 2023-06-22 US claimed
EP-4149483-A2 COMPOSITIONS AND METHODS FOR ENHANCING CANCER IMMUNOTHERAPY Fred Hutchinson Cancer Center (US) 2023-03-22 EP claimed
WO-2022165398-A1 METHODS FOR TREATING AND AMELIORATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 WO claimed
US-12623988-B2 Scaleable preparation of polyketides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-12 US disclosed
WO-2025151487-A2 SMALL-MOLECULE INHIBITORS OF ADAR1 REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2025-07-17 WO disclosed
JP-2025065209-A Methods for Treating and Ameliorating Cancer ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 2025-04-17 JP disclosed
US-12172988-B2 Anticancer and antifungal splice modulators THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-24 US disclosed
US-12172988-B2 Anticancer and antifungal splice modulators THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-24 US disclosed
WO-2024254465-A2 METHODS FOR PROMOTING EXPANSION OF HUMAN CD34+ CELLS IN VIVO AND FOR PROMOTING NEURAL REGENERATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-12 WO disclosed
WO-2007110705-A2 MACROLIDE AS INHIBITORS OF MHC CLASS II NOVIMMUNE SA (CH) 2007-10-04 WO disclosed
US-7256178-B2 Physiologically active substances EISAI CO., LTD. (JP) 2007-08-14 US disclosed
US-7256178-B2 Physiologically active substances EISAI CO., LTD. (JP) 2007-08-14 US disclosed
US-20060079572-A1 Novel bioactive substance MICROBIOPHARM JAPAN CO., LTD. (JP) 2006-04-13 US disclosed
US-7026352-B1 Physiologically active substances MERCIAN CORPORATION (JP) 2006-04-11 US disclosed
EP-1380579-A1 NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCES MERCIAN CORPORATION (JP) 2004-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060079572-A1 Novel bioactive substance CASP7, MMP7, BMP4 SF3B3 2363/4885
US-12623988-B2 Scaleable preparation of polyketides SF3B5, RPS5, RPS25 SF3B3 95/4885
US-12172988-B2 Anticancer and antifungal splice modulators SF3B5, U2AF1, CWC15 SF3B3 28/4885
US-20240148688-A1 METHODS FOR TREATING AND AMELIORATING CANCER ABL1, FLT3, MCL1 SF3B3 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.