Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 3/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.30 |
| ▸ | WEE1 | P30291 | 1/20 | 0.30 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.30 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1671031 | 0.86 | — | — | |
| SCHEMBL1671034 | 0.82 | — | — | |
| SCHEMBL1672972 | 0.81 | TSHR (0.41) | PKMYT1TSHRCREBBP | |
| SCHEMBL1670036 | 0.68 | PREP (0.31) | — | |
| SCHEMBL1670809 | 0.68 | BRD4 (0.34) | TSHRCREBBP | |
| SCHEMBL1670810 | 0.63 | BRD4 (0.34) | — | |
| SCHEMBL12800297 | 0.63 | BRD4 (0.38) | CREBBP | |
| SCHEMBL6650651 | 0.62 | POLB (0.50) | MKNK2TSHR | |
| SCHEMBL12989246 | 0.62 | HSP90AA1 (0.39) | TSHR | |
| SCHEMBL30386550 | 0.61 | ESR1 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |