Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.31 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670979 | 0.87 | SENP1 (0.31) | — | |
| SCHEMBL1671015 | 0.75 | MAP4K4 (0.32) | MAP4K4 | |
| SCHEMBL1670405 | 0.72 | KDM1A (0.30) | — | |
| SCHEMBL1670403 | 0.72 | KDM1A (0.30) | — | |
| SCHEMBL12801018 | 0.70 | SENP1 (0.33) | — | |
| SCHEMBL1671167 | 0.70 | ESR1 (0.34) | — | |
| SCHEMBL1671169 | 0.70 | ESR1 (0.34) | — | |
| SCHEMBL1670799 | 0.70 | SENP1 (0.31) | — | |
| SCHEMBL1672283 | 0.69 | ESR1 (0.32) | — | |
| SCHEMBL1672285 | 0.69 | ESR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |