Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670809 | 0.87 | BRD4 (0.34) | TSHRFTOARBRD4ALDH1A1 | |
| SCHEMBL1670805 | 0.87 | BRD4 (0.34) | TSHRFTOARBRD4ALDH1A1 | |
| SCHEMBL12800297 | 0.83 | BRD4 (0.38) | ARBRD4KMT2ABRD2CREBBP | |
| SCHEMBL1670810 | 0.82 | BRD4 (0.34) | FTOHSD17B10BRD4BRD2 | |
| SCHEMBL1670628 | 0.81 | PKMYT1 (0.34) | TSHRPKMYT1CREBBP | |
| SCHEMBL30386550 | 0.80 | ESR1 (0.39) | TSHRFTOARHSD17B10BRD4 | |
| SCHEMBL1075535 | 0.80 | ESR1 (0.39) | TSHRFTOARHSD17B10BRD4 | |
| SCHEMBL12989246 | 0.78 | HSP90AA1 (0.39) | TSHRARHSD17B10BRD4GAA | |
| SCHEMBL1670395 | 0.78 | BRD4 (0.36) | ARBRD4MEN1KMT2AALDH1A1 | |
| SCHEMBL1682440 | 0.78 | AR (0.39) | TSHRFTOARHSD17B10BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |