Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.40 |
| ▸ | BRD4 | O60885 | 6/20 | 0.39 |
| ▸ | TAS2R8 | Q9NYW2 | 5/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670571 | 0.85 | BRD4 (0.32) | ERN1BRD4TAS2R8 | |
| SCHEMBL1670574 | 0.85 | BRD4 (0.32) | ERN1BRD4TAS2R8 | |
| SCHEMBL1670909 | 0.85 | PTGS2 (0.40) | BRD4TAS2R8ALDH1A1BRD2 | |
| SCHEMBL1670669 | 0.76 | BRD4 (0.32) | BRD4TAS2R8EDNRA | |
| SCHEMBL1670663 | 0.75 | BRD4 (0.32) | BRD4 | |
| SCHEMBL1670665 | 0.75 | BRD4 (0.32) | BRD4 | |
| SCHEMBL1671281 | 0.69 | BRD4 (0.33) | ERN1BRD4ALDH1A1 | |
| SCHEMBL1671278 | 0.69 | BRD4 (0.33) | ERN1BRD4ALDH1A1 | |
| SCHEMBL1670945 | 0.65 | BRD4 (0.34) | ERN1BRD4TTR | |
| SCHEMBL1670948 | 0.65 | BRD4 (0.34) | ERN1BRD4TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |