Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22878973 | 1.00 | EPHX1 (0.39) | EPHX1GPR84HDAC3HDAC1HDAC2 | |
| SCHEMBL24485285 | 0.85 | CYP1A2 (0.39) | ALDH1A1MAPT | |
| SCHEMBL22754631 | 0.84 | TSHR (0.40) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL22301648 | 0.84 | POLB (0.41) | GPR84ALDH1A1MAPT | |
| SCHEMBL25025146 | 0.84 | POLB (0.41) | GPR84ALDH1A1MAPT | |
| SCHEMBL31163657 | 0.84 | POLB (0.41) | GPR84ALDH1A1MAPT | |
| SCHEMBL24806136 | 0.77 | HDAC3 (0.32) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL31163671 | 0.77 | PPARA (0.41) | — | |
| SCHEMBL14617942 | 0.77 | CYP1A2 (0.33) | — | |
| SCHEMBL24807518 | 0.77 | ALDH1A1 (0.42) | EPHX1GPR84ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512163-B2 | Compositions and methods for conjugating oligonucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150133631-A1 | Compositions and Methods for Conjugating Oligonucleotides | AGILENT TECHNOLOGIES, INC. | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133631-A1 | Compositions and Methods for Conjugating Oligonucleotides | DCLRE1A, NR0B1, NR0B2 | EPHX1 3320/4885GPR84 457/4885HDAC3 1383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.