SCHEMBL16707396

SCHEMBL16707396

Cc1ccc(C)c(N=C=O)c1C

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.46
TRPA1 O75762 1/20 0.45
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
TDP2 O95551 1/20 0.33
NSD2 O96028 1/20 0.33
HSP90AA1 P07900 1/20 0.33
PAX8 Q06710 1/20 0.33
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL295649 0.87 CYP3A4 (0.50) CYP3A4TRPA1GABRA1GABRB2TSHR
SCHEMBL291584 0.85 CYP3A4 (0.57) CYP3A4TRPA1GABRA1GABRB2TDP1
SCHEMBL29930513 0.85 CYP3A4 (0.52) CYP3A4TRPA1GABRA1GABRB2TDP2
SCHEMBL110656 0.85 CYP3A4 (0.52) CYP3A4TRPA1GABRA1GABRB2TDP2
SCHEMBL20893283 0.85 CYP3A4 (0.42) CYP3A4TRPA1GABRA1GABRB2TSHR
SCHEMBL7330225 0.83 GABRA1 (0.42) CYP3A4TRPA1GABRA1GABRB2TDP1
SCHEMBL10732712 0.80 ALDH1A1 (0.43) CYP3A4TRPA1GABRA1GABRB2TSHR
SCHEMBL14718233 0.78 CYP3A4 (0.37) CYP3A4TRPA1GABRA1GABRB2HSP90AA1
SCHEMBL1482064 0.78 CYP3A4 (0.37) CYP3A4TRPA1GABRA1GABRB2HSP90AA1
SCHEMBL5427471 0.78 CYP3A4 (0.43) CYP3A4TRPA1GABRA1GABRB2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9647218-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-05-09 US disclosed
US-20150129849-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-05-14 US disclosed