SCHEMBL16707477

SCHEMBL16707477

Cc1cc(SC#N)c(C)cc1SC#N

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.44
USP8 P40818 1/20 0.44
USP5 P45974 1/20 0.44
USP4 Q13107 1/20 0.44
USP7 Q93009 1/20 0.44
ALDH1A1 P00352 7/20 0.38
MAPT P10636 6/20 0.38
HTT P42858 1/20 0.38
LMNA P02545 2/20 0.34
HPGD P15428 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
GFER P55789 1/20 0.33
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16707476 0.95 USP2 (0.41) USP2USP8USP5USP4USP7
SCHEMBL2034128 0.87 ALDH1A1 (0.43) USP2USP8USP5USP4USP7
SCHEMBL11374139 0.84 USP2 (0.47) USP2USP8USP5USP4USP7
SCHEMBL19773972 0.84 USP2 (0.38) USP2USP8USP5USP4USP7
SCHEMBL16707519 0.80 USP2 (0.39) USP2USP8USP5USP4USP7
SCHEMBL16707552 0.79 ALDH1A1 (0.33) USP2USP8USP5USP4USP7
SCHEMBL30673282 0.79 HAO1 (0.43) USP2USP8USP5USP4USP7
SCHEMBL7939185 0.79 MEN1 (0.39) USP2USP8USP5USP4USP7
SCHEMBL10897641 0.79 HAO1 (0.43) USP2USP8USP5USP4USP7
SCHEMBL7459101 0.77 ALDH1A1 (0.44) USP2USP8USP5USP4USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9647218-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-05-09 US disclosed
US-20150129849-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-05-14 US disclosed