Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | USP8 | P40818 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | USP4 | Q13107 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 6/20 | 0.36 |
| ▸ | HTR3A | P46098 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10897641 | 1.00 | HAO1 (0.43) | HAO1ALDH1A1MEN1HPGDALOX15 | |
| SCHEMBL7939185 | 0.83 | MEN1 (0.39) | HAO1ALDH1A1MEN1HPGDALOX15 | |
| SCHEMBL21396252 | 0.81 | ALDH1A1 (0.41) | HAO1ALDH1A1USP2USP8USP5 | |
| SCHEMBL16707551 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL5635870 | 0.79 | ESR2 (0.39) | ALDH1A1HPGDALOX15USP2USP8 | |
| SCHEMBL21564138 | 0.79 | PKM (0.37) | ALDH1A1MEN1HPGDALOX15ALOX12 | |
| SCHEMBL21318164 | 0.79 | USP2 (0.35) | ALDH1A1KMT2AHSD17B10USP2USP8 | |
| SCHEMBL20228268 | 0.79 | USP2 (0.35) | HAO1ALDH1A1MEN1HPGDALOX15 | |
| SCHEMBL16707477 | 0.79 | USP2 (0.44) | ALDH1A1HPGDUSP2USP8USP5 | |
| SCHEMBL8131924 | 0.75 | NPC1 (0.53) | ALDH1A1MEN1HPGDALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024376-B | Preparation method of hydrobromic acid voltammetric acid duloxetine | 寿光富康制药有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-117024376-A | Preparation method of hydrobromic acid voltammetric acid duloxetine | 寿光富康制药有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-117024376-B | Preparation method of hydrobromic acid voltammetric acid duloxetine | 寿光富康制药有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-117024376-A | Preparation method of hydrobromic acid voltammetric acid duloxetine | 寿光富康制药有限公司 | 2023-11-10 | — | — | CN | disclosed |