SCHEMBL167075

SCHEMBL167075

C=CCc1cccc(CC=C)c1N

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.54
GABRB2 P47870 2/20 0.54
AKR1B1 P15121 1/20 0.41
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
MAPT P10636 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 4/20 0.37
GAA P10253 3/20 0.37
LMNA P02545 2/20 0.37
KDM4E B2RXH2 2/20 0.34
CASP1 P29466 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
ALOX12 P18054 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10985482 0.91 GABRA1 (0.47) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL11829879 0.89 GABRA1 (0.50) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL11428422 0.89 GABRA1 (0.46) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL30582776 0.89 GABRA1 (0.48) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL1072787 0.89 GABRA1 (0.48) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL7751350 0.85 GABRA1 (0.46) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL174595 0.85 GABRA1 (0.55) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL11499257 0.85 GABRA1 (0.46) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL1646862 0.83 GABRA1 (0.53) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL11665569 0.83 GABRA1 (0.44) GABRA1GABRB2AKR1B1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117659099-A Alpha-carboxyl-beta-diimine nickel complex, preparation method and application thereof, and preparation method of ethylene-methyl acrylate copolymer 中国石油天然气股份有限公司 2024-03-08 CN claimed
CN-116943724-A Supported catalyst, preparation method thereof and synthesis method of N-alkoxyalkyl-2, 6-dialkylaniline 华茂伟业绿色科技股份有限公司 2023-10-27 CN claimed
CN-110041456-B Supported catalyst for preparing polypropylene elastomer montmorillonite composite material and preparation method thereof 中国石油天然气股份有限公司 2021-08-31 CN claimed
JP-4808625-B2 2011-11-02 JP claimed
EP-1971568-B1 PROCESS FOR CONTINUOUS PREPARATION OF A PRIMARY AROMATIC AMINE BASF SE (DE) 2011-08-03 EP claimed
US-7767855-B2 Method for the continuous production of an amine BASF SE (DE) 2010-08-03 US claimed
WO-2009141215-A1 TWO-COMPONENT COMPOSITION FOR PRODUCING FLEXIBLE POLYURETHANE GELCOATS EVONIK DEGUSSA GMBH (DE) 2009-11-26 WO claimed
US-20090076306-A1 PROCESS FOR CONTINUOUS PREPARATION OF A PRIMARY AROMATIC AMINE BASF SE (DE) 2009-03-19 US claimed
EP-1899291-B1 METHOD FOR THE CONTINUOUS PRODUCTION OF AN AMINE BASF SE (DE) 2009-03-18 EP claimed
EP-1684901-A4 DIIMINE LIGAND, METAL COMPOUND, OLEFIN POLYMERIZATION PROCESS FINA TECHNOLOGY (US) 2008-09-03 EP claimed
EP-0052817-A1 Process for the preparation of 4-chloro-2,6 dialkyl anilines BAYER AG (DE) 1982-06-02 EP claimed
EP-0004958-B1 PROCESS FOR THE PREPARATION OF 2,6-DIALKYL-N-ALKYLANILINES CIBA-GEIGY AG (CH) 1982-05-26 EP claimed
EP-0003304-B1 PROCESS FOR THE PREPARATION OF N-SUBSTITUTED 2,6-DIALKYL ANILINES BASF Aktiengesellschaft (DE) 1981-11-25 EP claimed
US-4267356-A Process for the preparation of N-(1'-alkoxycarbonylethyl)-2,6-dialkylanilines CIBA-GEIGY CORPORATION (US) 1981-05-12 US claimed
US-4266071-A Process for the preparation of N-(1-alkoxycarbonylethyl)-2,6-dialkylanilines CIBA-GEIGY CORPORATION (US) 1981-05-05 US claimed
US-4260782-A Process for the preparation of N-(1'-alkoxycarbonylethyl)-2,6-dialkylanilines CIBA-GEIGY CORPORATION (US) 1981-04-07 US claimed
US-4255587-A CARBONYLATION OF 2,6-DIALKYLANILINES USING AN OXO-SUBSTITUTED ESTER FOLLOWED BY CATALYTIC HYDROGENATION BASF AKTIENGESELLSCHAFT (DE) 1981-03-10 US claimed
US-4219503-A ALKYLATION OF AROMATIC AMINE, ALUMINUM ANILIDE TYPE CATALYST ETHYL CORPORATION (US) 1980-08-26 US claimed
US-4183868-A COPPER CONTAINING ALKYLATION CATALYST CIBA-GEIGY CORPORATION (US) 1980-01-15 US claimed
EP-0003304-A2 Process for the preparation of N-substituted 2,6-dialkyl anilines BASF Aktiengesellschaft (DE) 1979-08-08 EP claimed