SCHEMBL174595

SCHEMBL174595

C=CCc1cccc(O)c1N

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.55
GABRB2 P47870 3/20 0.55
AKR1B1 P15121 2/20 0.46
KMT2A Q03164 6/20 0.42
MEN1 O00255 5/20 0.42
MAPT P10636 4/20 0.42
GAA P10253 4/20 0.42
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
CASP1 P29466 1/20 0.42
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
MAPK1 P28482 1/20 0.41
POLB P06746 1/20 0.40
LMNA P02545 2/20 0.39
ALOX12 P18054 1/20 0.38
XDH P47989 1/20 0.38
G6PD P11413 1/20 0.38
CASP7 P55210 1/20 0.38
CASP6 P55212 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL167075 0.85 GABRA1 (0.54) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL20340223 0.81 ALDH1A1 (0.41) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL15349328 0.80 G6PD (0.42) GABRA1GABRB2AKR1B1KDM4EG6PD
SCHEMBL11829879 0.80 GABRA1 (0.50) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL1072787 0.79 GABRA1 (0.48) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL30582776 0.79 GABRA1 (0.48) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL30443762 0.79 GABRA1 (0.59) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL346369 0.79 GABRA1 (0.70) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL28552471 0.79 GABRA1 (0.59) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL30817860 0.79 GABRA1 (0.70) GABRA1GABRB2AKR1B1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4298165-A1 CURABLE FILM-FORMING COMPOSITIONS DEMONSTRATING ADHESION TO DIVERSE SUBSTRATES AND FAST SANDABILITY PPG Industries Ohio Inc. (US) 2024-01-03 EP claimed
CN-114262335-B Super-resolution self-flashing dye of targeting lysosome, and synthetic method and biological application thereof 中国科学院大连化学物理研究所 2023-07-04 CN claimed
CN-110582487-B Curable resin system 亨斯迈先进材料美国有限责任公司 2023-06-30 CN claimed
CN-114262335-A Lysosome-targeted super-resolution self-flashing dye and synthesis method and biological application thereof 中国科学院大连化学物理研究所 2022-04-01 CN claimed
CN-110240681-B Composite demulsifier, composition and application thereof 中国石油化工股份有限公司 2022-03-11 CN claimed
US-20200123310-A1 Curable Resin System HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2020-04-23 US claimed
EP-3612521-A1 CURABLE RESIN SYSTEM Huntsman Advanced Materials Americas LLC (US) 2020-02-26 EP claimed
CN-110582487-A Curable resin system 亨斯迈先进材料美国有限责任公司 2019-12-17 CN claimed
WO-2018195192-A1 CURABLE RESIN SYSTEM HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2018-10-25 WO claimed
EP-1851292-B1 LUBRICANT ADDITIVE FORMULATION CONTAINING MULTIFUNCTIONAL DISPERSANT LUBRIZOL CORP (US) 2017-08-30 EP claimed
WO-2008014315-A2 METHOD OF LUBRICATING AND LUBRICATING COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2008-01-31 WO claimed
WO-2007127661-A1 STAR POLYMER LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2007-11-08 WO claimed
EP-1851292-A1 LUBRICANT ADDITIVE FORMULATION CONTAINING MULTIFUNCTIONAL DISPERSANT THE LUBRIZOL CORPORATION (US) 2007-11-07 EP claimed
WO-2006091371-A1 LUBRICANT ADDITIVE FORMULATION CONTAINING MULTIFUNCTIONAL DISPERSANT THE LUBRIZOL CORPORATION (US) 2006-08-31 WO claimed
JP-2005528476-A 2005-09-22 JP claimed
US-20050130856-A1 Lubricant composition suitable for direct fuel injected, crankcase-scavenged two-stroke engines LUBRIZOL CORPORATION, THE 2005-06-16 US claimed
EP-1497399-A1 LUBRICANT COMPOSITION SUITABLE FOR DIRECT FUEL INJECTED, CRANKCASE-SCAVENGED TWO-STROKE ENGINES THE LUBRIZOL CORPORATION (US) 2005-01-19 EP claimed
WO-2003089555-A1 LUBRICANT COMPOSITION SUITABLE FOR DIRECT FUEL INJECTED, CRANKCASE-SCAVENGED TWO-STROKE ENGINES THE LUBRIZOL CORPORATION (US) 2003-10-30 WO claimed
CN-1385847-A Green light high-density recordable digital optical disk and preparation method thereof SHANGHAI INST OPTICS & FINE ME (CN) 2002-12-18 CN claimed
EP-0065733-B1 PROCESS FOR PREPARING 3-ALKYLAMINOPHENOLS HOECHST AKTIENGESELLSCHAFT (DE) 1984-07-11 EP claimed