SCHEMBL1670771

SCHEMBL1670771

O=CCCC(O)C(=O)CCCO

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CAMK2A Q9UQM7 1/20 0.34
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16505762 0.85 HIF1A (0.32)
SCHEMBL60126 0.81 CAMK2A (0.42) CAMK2A
SCHEMBL17512854 0.78 ALDH1A1 (0.39)
SCHEMBL2638024 0.73 CAMK2A (0.36) CAMK2A
SCHEMBL16592189 0.73
SCHEMBL8450101 0.72 GPR84 (0.46)
SCHEMBL3641049 0.70 PTPN1 (0.38)
SCHEMBL8386657 0.69
SCHEMBL1714630 0.67 HIF1A (0.43) CAMK2A
SCHEMBL11884343 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180142269-A1 MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL GENOMATICA INC (US) 2018-05-24 US disclosed
US-20110229946-A1 MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL, 4-HYDROXYBUTANAL, 4-HYDROXYBUTYRYL-COA, PUTRESCINE AND RELATED COMPOUNDS, AND METHODS RELATED THERETO GENOMATICA, INC. (US) 2011-09-22 US disclosed
US-20110129899-A1 MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL, 4-HYDROXYBUTANAL, 4-HYDROXYBUTYRYL-COA, PUTRESCINE AND RELATED COMPOUNDS, AND METHODS RELATED THERETO AGAIN BIO APS (DK) 2011-06-02 US disclosed
WO-2011047101-A1 MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL, 4-HYDROXYBUTANAL, 4-HYDROXYBUTYRYL-COA, PUTRESCINE AND RELATED COMPOUNDS, AND METHODS RELATED THERETO GENOMATICA, INC. (US) 2011-04-21 WO disclosed