SCHEMBL16708448

SCHEMBL16708448

C=CC(=O)OC12CC3CC(C1)CC(C(C)(C)OC(=O)C=C)(C3)C2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 1/20 0.31
DPP9 Q86TI2 1/20 0.31
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16708440 0.89
SCHEMBL16708442 0.89 DPP8 (0.31) DPP8DPP9
SCHEMBL5901413 0.89 MEN1 (0.32) MEN1MAPK1KMT2A
SCHEMBL23974125 0.86 DPP8 (0.32) DPP8DPP9
SCHEMBL1028437 0.83 PKM (0.33)
SCHEMBL1027385 0.83 TSHR (0.36)
SCHEMBL5900845 0.83
SCHEMBL332873 0.82 MEN1 (0.36) MEN1MAPK1KMT2A
SCHEMBL2208058 0.82 MEN1 (0.36) DPP8DPP9MEN1MAPK1KMT2A
SCHEMBL29281840 0.82 MEN1 (0.30) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9376621-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-28 US disclosed
US-9376621-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-28 US disclosed
US-20150129801-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-05-14 US disclosed
US-20150129801-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150129801-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE BACE1, DRD1, CHRM1 DPP8 2508/4885DPP9 2432/4885MEN1 1095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.