SCHEMBL16709765

SCHEMBL16709765

CC(OCC1CO1)c1ccc(Sc2ccc3ccccc3c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 3/20 0.37
POLB P06746 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HIF1A Q16665 1/20 0.36
CHRM2 P08172 2/20 0.35
CHRM4 P08173 2/20 0.35
CHRM5 P08912 2/20 0.35
CHRM1 P11229 2/20 0.35
CHRM3 P20309 2/20 0.35
UGT2B7 P16662 1/20 0.35
GLA P06280 1/20 0.35
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
KCNH2 Q12809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16709774 0.88 CHRM2 (0.44) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL16709689 0.84 ALDH1A1 (0.35) TDP1ALDH1A1POLBL3MBTL1TP53
SCHEMBL16709681 0.83 SLC6A4 (0.35) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL9235403 0.78 TDP1 (0.50) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL16709687 0.77 CHRM2 (0.39) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL16709785 0.75 LMNA (0.40) TDP1ALDH1A1POLBL3MBTL1TP53
SCHEMBL2476049 0.72 ALDH1A1 (0.37) TDP1ALDH1A1POLBTP53CYP3A4
SCHEMBL12202111 0.72 ALDH1A1 (0.37) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL28033823 0.70 TDP1 (0.54) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL16709688 0.70 ALDH1A1 (0.39) TDP1ALDH1A1POLBL3MBTL1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015068839-A1 POLYMERIZABLE COMPOUND, RESIN COMPOSITION USING SAME, CURED RESIN, AND OPTICAL MATERIAL 新日鉄住金化学株式会社 2015-05-14 WO disclosed