Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 5/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1671022 | 1.00 | KDM1A (0.35) | KDM1AMGLLESR1ESR2TTR | |
| SCHEMBL1670273 | 0.86 | BRD4 (0.33) | KDM1ATTRERN1 | |
| SCHEMBL1670272 | 0.86 | BRD4 (0.33) | KDM1ATTRERN1 | |
| SCHEMBL1671024 | 0.82 | TTR (0.34) | ESR1ESR2TTRARMIF | |
| SCHEMBL1670804 | 0.82 | TTR (0.34) | ESR1ESR2TTRAR | |
| SCHEMBL1670802 | 0.82 | TTR (0.34) | ESR1ESR2TTRAR | |
| SCHEMBL1670517 | 0.81 | KDM1A (0.33) | KDM1AMGLLESR1ESR2TTR | |
| SCHEMBL1671189 | 0.80 | ERN1 (0.34) | MGLLESR1ESR2TTRAR | |
| SCHEMBL1671187 | 0.80 | ERN1 (0.34) | MGLLESR1ESR2TTRAR | |
| SCHEMBL1672789 | 0.73 | ERN1 (0.38) | KDM1AMGLLESR1ESR2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |