SCHEMBL1672789 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	ERN1	O75460	2/20	0.38

▸	KDM1A	O60341	2/20	0.34

▸	MLYCD	O95822	1/20	0.34

▸	BRD4	O60885	9/20	0.34

▸	MGLL	Q99685	4/20	0.34

▸	ESR1	P03372	1/20	0.34

▸	ESR2	Q92731	1/20	0.34

▸	BTK	Q06187	1/20	0.34

▸	BRD2	P25440	3/20	0.33

▸	BRD3	Q15059	2/20	0.33

▸	NSD3	Q9BZ95	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1672787	1.00	ERN1 (0.38)	ERN1KDM1AMLYCDBRD4MGLL
SCHEMBL1672805	0.85	BRD4 (0.38)	ERN1MLYCDBRD4BRD2
SCHEMBL1672807	0.85	BRD4 (0.38)	ERN1MLYCDBRD4BRD2
SCHEMBL1672861	0.83	BRD4 (0.38)	ERN1MLYCDBRD4BTKBRD2
SCHEMBL1672863	0.83	BRD4 (0.38)	ERN1MLYCDBRD4BTKBRD2
SCHEMBL1670492	0.83	BRD4 (0.35)	ERN1BRD4ESR1ESR2BTK
SCHEMBL11898800	0.82	ERN1 (0.38)	ERN1KDM1AMLYCDBRD4MGLL
SCHEMBL1682416	0.82	ERN1 (0.38)	ERN1KDM1AMLYCDBRD4MGLL
SCHEMBL1672792	0.82	ERN1 (0.38)	ERN1MLYCDBRD4BRD2BRD3
SCHEMBL1672986	0.80	ERN1 (0.40)	ERN1KDM1AMLYCDBRD4MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011042477-A1	SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS	KARO BIO AB (SE)	2011-04-14	—	—	WO	disclosed