Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26421920 | 0.89 | F2 (0.53) | F2KCNH3KDM4EALDH1A1FDPS | |
| SCHEMBL14982724 | 0.81 | KCNH3 (0.51) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL13450943 | 0.81 | F2 (0.50) | F2ABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL30800855 | 0.81 | ABCB11 (0.49) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL9015900 | 0.81 | KCNH3 (0.51) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL18394327 | 0.79 | ABCB11 (0.47) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL15922729 | 0.79 | F2 (0.44) | F2ABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL11559744 | 0.75 | MAPK14 (0.37) | F2CYP3A4KDM4ERECQLALDH1A1 | |
| SCHEMBL18419361 | 0.75 | ABCB11 (0.44) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL18419346 | 0.75 | ABCB11 (0.44) | ABCB11CYP3A4ADRA2BOPRD1SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2873711-A1 | Platinum complexes | Centre National de la Recherche Scientifique (C.N.R.S.) (FR) | 2015-05-20 | — | — | EP | disclosed |