Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 19/20 | 1.00 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16712528 | 0.85 | KHK (0.73) | KHK | |
| SCHEMBL2564804 | 0.81 | KHK (0.69) | KHK | |
| SCHEMBL16712539 | 0.75 | KHK (1.00) | KHK | |
| SCHEMBL16712463 | 0.74 | KHK (1.00) | KHKKCNH2 | |
| SCHEMBL626660 | 0.74 | KCNJ1 (0.72) | KHKKCNJ1KCNH2 | |
| SCHEMBL2547130 | 0.74 | KHK (0.58) | KHK | |
| SCHEMBL2549642 | 0.74 | KHK (0.57) | KHK | |
| Hydrochloric Acid SCHEMBL6289818 | 0.73 | KCNJ1 (0.70) | KHKKCNJ1KCNH2 | |
| Hydrochloric Acid SCHEMBL4478110 | 0.73 | KCNJ1 (0.70) | KHKKCNJ1KCNH2 | |
| SCHEMBL5334337 | 0.73 | KCNJ1 (0.70) | KHKKCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560962-B1 | INDAZOLE COMPOUNDS USEFUL AS KETOHEXOKINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-05-20 | — | — | EP | disclosed |