Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16712468 | 0.85 | KHK (1.00) | KHK | |
| SCHEMBL12239964 | 0.74 | KHK (1.00) | KHK | |
| Hydrochloric Acid SCHEMBL2548617 | 0.73 | KHK (0.98) | KHK | |
| SCHEMBL16712487 | 0.72 | KHK (1.00) | KHK | |
| SCHEMBL16712543 | 0.71 | KHK (1.00) | KHK | |
| SCHEMBL16712519 | 0.71 | KHK (1.00) | KHK | |
| SCHEMBL16712527 | 0.71 | KHK (1.00) | KHK | |
| SCHEMBL2550280 | 0.71 | KHK (0.60) | KHK | |
| SCHEMBL1578113 | 0.71 | SIGMAR1 (0.66) | — | |
| SCHEMBL2548968 | 0.70 | KHK (0.51) | KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560962-B1 | INDAZOLE COMPOUNDS USEFUL AS KETOHEXOKINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-05-20 | — | — | EP | disclosed |