Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 12/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4437577 | 0.82 | PIK3CD (0.43) | PIK3CDP2RX7CCR1CCR8L3MBTL1 | |
| SCHEMBL4432811 | 0.82 | PIK3CD (0.43) | PIK3CDP2RX7CCR1CCR8L3MBTL1 | |
| SCHEMBL4441908 | 0.82 | PIK3CD (0.45) | PIK3CDP2RX7CCR1CCR8L3MBTL1 | |
| SCHEMBL16712478 | 0.79 | PDE2A (0.37) | PIK3CDCCR1CCR8L3MBTL1PIK3CG | |
| SCHEMBL15363592 | 0.77 | PIK3CD (0.41) | PIK3CDCCR1CCR8L3MBTL1PIK3CG | |
| SCHEMBL4178020 | 0.76 | CCR1 (0.39) | PIK3CDCCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL10251837 | 0.75 | PIK3CD (0.43) | PIK3CDCCR1CCR8L3MBTL1PIK3CG | |
| SCHEMBL16712452 | 0.74 | P2RX7 (0.35) | PIK3CDP2RX7PTGS2 | |
| Hydrochloric Acid SCHEMBL4174758 | 0.74 | PIK3CD (0.43) | PIK3CDCCR1CCR8L3MBTL1PIK3CG | |
| SCHEMBL4175840 | 0.74 | PIK3CD (0.45) | PIK3CDP2RX7CCR1CCR8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614061-B1 | QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2015-05-20 | — | — | EP | disclosed |