Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13410176 | 0.94 | TGM2 (0.41) | HTR2ASSTR3TGM2PTPN1SIRT2 | |
| SCHEMBL13401556 | 0.94 | TGM2 (0.41) | HTR2ASSTR3TGM2PTPN1SIRT2 | |
| SCHEMBL29522978 | 0.93 | FURIN (0.37) | HTR2ASSTR3PTPN1SIRT2SIRT1 | |
| SCHEMBL31681402 | 0.90 | PTPN1 (0.40) | HTR2ATPSAB1TGM2PTPN1SIRT2 | |
| SCHEMBL12094377 | 0.89 | HTR2A (0.40) | HTR2ASSTR3PTPN1SIRT2SIRT1 | |
| SCHEMBL2734925 | 0.89 | HTR2A (0.40) | HTR2ASSTR3PTPN1SIRT2SIRT1 | |
| SCHEMBL13830646 | 0.89 | HTR2A (0.40) | HTR2ASSTR3PTPN1SIRT2SIRT1 | |
| SCHEMBL19731720 | 0.89 | HTR2A (0.40) | HTR2ASSTR3PTPN1SIRT2SIRT1 | |
| SCHEMBL12944195 | 0.89 | HTR2A (0.40) | HTR2ASSTR3PTPN1SIRT2SIRT1 | |
| SCHEMBL29579452 | 0.89 | HTR2A (0.40) | HTR2ASSTR3PTPN1SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015069587-A2 | PEPTIDE CONTAINING CONJUGATES FOR DUAL MOLECULAR DELIVERY OF OLIGONUCLEOTIDES | MERCK SHARP & DOHME CORP. (US) | 2015-05-14 | — | — | WO | disclosed |