SCHEMBL19731720

SCHEMBL19731720

CC(C)C(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NC(CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 1/20 0.40
▸ PTPN1 P18031 4/20 0.39
▸ FURIN P09958 2/20 0.39
▸ SSTR3 P32745 1/20 0.38
▸ CASP3 P42574 2/20 0.38
▸ SIRT2 Q8IXJ6 5/20 0.38
▸ SIRT1 Q96EB6 3/20 0.38
▸ SIRT3 Q9NTG7 3/20 0.38
▸ MAP1LC3B Q9GZQ8 1/20 0.37
▸ SIRT5 Q9NXA8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12944195 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL29414597 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL29579452 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL13110590 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL2734925 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL12094377 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL13830646 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
Trifluoroacetic Acid SCHEMBL31096968 0.96 PTPN1 (0.43) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL15088221 0.96 HTR2A (0.40) HTR2APTPN1SSTR3SIRT2SIRT1
SCHEMBL13311064 0.94 FURIN (0.39) HTR2APTPN1FURINSSTR3SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034220-A1 ANTI-CEA IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2026-02-05 — — US disclosed
US-12514926-B2 Splicing modulator antibody-drug conjugates and methods of use EISAI R&D MANAGEMENT CO., LTD. (JP) 2026-01-06 — — US disclosed
US-20250276074-A1 BRM AND BRG1 TARGETING ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF PRELUDE THERAPEUTICS INCORPORATED 2025-09-04 — — US disclosed
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-07-03 — — US disclosed
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2025-06-05 — — US disclosed
US-12304925-B2 Tetragalnac and peptide containing conjugates and methods for delivery of oligonucleotides SIRNA THERAPEUTICS, INC. (US) 2025-05-20 — — US disclosed
US-20250135017-A1 SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-05-01 — — US disclosed
WO-2025051241-A1 MACROCYCLIC COMPOUND AND ANTIBODY-DRUG CONJUGATE THEREOF 劲方医药科技(上海)股份有限公司 2025-03-13 — — WO disclosed
US-12172986-B2 Splicing modulator antibody-drug conjugates and methods of use EISAI R&D MANAGEMENT CO., LTD (JP) 2024-12-24 — — US disclosed
US-20240360108-A1 SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-10-31 — — US disclosed
EP-3468996-B1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2022-05-04 — — EP disclosed
EP-3980423-A1 5H-PYRROLO[3,2-D]PYRIMIDINE-2,4-DIAMINO COMPOUNDS AND ANTIBODY CONJUGATES THEREOF Sutro Biopharma, Inc. (US) 2022-04-13 — — EP disclosed
EP-3966229-A1 GLYCOPEPTIDE VACCINE Victoria Link Ltd (NZ) 2022-03-16 — — EP disclosed
EP-3856258-A1 SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES PIERRE FABRE MEDICAMENT (FR) 2021-08-04 — — EP disclosed
EP-3801632-A1 SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE Eisai R&D Management Co., Ltd. (JP) 2021-04-14 — — EP disclosed
WO-2020252043-A1 5H-PYRROLO[3,2-d]PYRIMIDINE-2,4-DIAMINO COMPOUNDS AND ANTIBODY CONJUGATES THEREOF SUTRO BIOPHARMA, INC. (US) 2020-12-17 — — WO disclosed
WO-2020231274-A1 GLYCOPEPTIDE VACCINE VICTORIA LINK LTD (NZ) 2020-11-19 — — WO disclosed
WO-2019232449-A9 SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2020-09-24 — — WO disclosed
WO-2020065408-A1 SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES PIERRE FABRE MEDICAMENT (FR) 2020-04-02 — — WO disclosed
US-20170360951-A1 BIOLOGICAL MATERIALS AND USES THEREOF ANTIKOR BIOPHARMA LIMITED (GB) 2017-12-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360108-A1 SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE RBM17, RBM22, SF3B1 HTR2A 3646/4885PTPN1 1896/4885FURIN 2401/4885
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 HTR2A 3707/4885PTPN1 400/4885FURIN 2449/4885
US-20260034220-A1 ANTI-CEA IMMUNOCONJUGATES, AND USES THEREOF IL2, CD47, EPCAM HTR2A 813/4885PTPN1 3213/4885FURIN 1312/4885
US-12172986-B2 Splicing modulator antibody-drug conjugates and methods of use RBM17, RBM22, SF3B1 HTR2A 3646/4885PTPN1 1896/4885FURIN 2401/4885
US-20250135017-A1 SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE RBM17, SNRPE, HNRNPAB HTR2A 3925/4885PTPN1 2120/4885FURIN 3243/4885
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 HTR2A 4369/4885PTPN1 851/4885FURIN 2314/4885
US-20250276074-A1 BRM AND BRG1 TARGETING ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF CRBN, RBX1, SMARCE1 HTR2A 3981/4885PTPN1 4059/4885FURIN 3060/4885
US-12304925-B2 Tetragalnac and peptide containing conjugates and methods for delivery of oligonucleotides GALNT3, B3GAT3, CSGALNACT1 HTR2A 4659/4885PTPN1 2620/4885FURIN 996/4885
US-20170360951-A1 BIOLOGICAL MATERIALS AND USES THEREOF CD47, LNPEP, TIE1 HTR2A 4199/4885PTPN1 1495/4885FURIN 102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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