Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | OXTR | P30559 | 1/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.52 |
| ▸ | CD81 | P60033 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | USP7 | Q93009 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.52 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16713189 | 1.00 | PTPN1 (0.61) | PTPN1PTPN2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL4737967 | 0.88 | PTPN1 (0.64) | PTPN1PTPN2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL4737968 | 0.88 | PTPN1 (0.64) | PTPN1PTPN2ALOX5AKR1B10AKR1B1 | |
| Primulagenin SCHEMBL1050073 | 0.87 | PTPN1 (0.75) | PTPN1PTPN2ALOX5AKR1B10AKR1B1 | |
| Primulagenin SCHEMBL179854 | 0.87 | PTPN1 (0.75) | PTPN1PTPN2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL1050549 | 0.86 | ALOX5 (0.75) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL16713179 | 0.85 | PTPN1 (0.76) | PTPN1PTPN2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL16713178 | 0.85 | PTPN1 (0.76) | PTPN1PTPN2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL16713198 | 0.82 | PTPN1 (0.63) | PTPN1PTPN2ALOX5AKR1B10AKR1B1 | |
| SCHEMBL16713199 | 0.82 | PTPN1 (0.63) | PTPN1PTPN2ALOX5AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994883-B2 | Triterpenoid sapogenin production in plant and microbial cultures | VIB VZW (BE) | 2018-06-12 | — | — | US | disclosed |
| US-20150141633-A1 | TRITERPENOID SAPOGENIN PRODUCTION IN PLANT AND MICROBIAL CULTURES | UNIVERSITEIT GENT (BE) | 2015-05-21 | — | — | US | disclosed |