Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.63 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | F3 | P13726 | 5/20 | 0.59 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | OXTR | P30559 | 1/20 | 0.59 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.59 |
| ▸ | CD81 | P60033 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | USP7 | Q93009 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.58 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.54 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.54 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737968 | 1.00 | PTPN1 (0.64) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| Primulagenin SCHEMBL1050073 | 0.93 | PTPN1 (0.75) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| Primulagenin SCHEMBL179854 | 0.93 | PTPN1 (0.75) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL1050549 | 0.92 | ALOX5 (0.75) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL16713188 | 0.88 | PTPN1 (0.61) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL16713189 | 0.88 | PTPN1 (0.61) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL4739790 | 0.83 | CYP3A4 (0.65) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL4739787 | 0.83 | CYP3A4 (0.65) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| Primulagenin SCHEMBL8165311 | 0.82 | PTPN1 (0.69) | PTPN1AKR1B10AKR1B1F3SIRT5 | |
| SCHEMBL13621821 | 0.82 | PTPN1 (0.74) | PTPN1ALOX5AKR1B10AKR1B1F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071169-A2 | METHOD FOR THE PRODUCTION OF SPECIFIC INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE, IN PARTICULAR TYPE 1 WITH BASIC NOR-OLEANAN OR NOR-URSAN FRAMEWORKS | UNIVERSITÄTSKLINIKUM SCHLESWIG-HOLSTEIN (DE) | 2008-06-19 | — | — | WO | claimed |
| WO-2008071169-A2 | METHOD FOR THE PRODUCTION OF SPECIFIC INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE, IN PARTICULAR TYPE 1 WITH BASIC NOR-OLEANAN OR NOR-URSAN FRAMEWORKS | UNIVERSITÄTSKLINIKUM SCHLESWIG-HOLSTEIN (DE) | 2008-06-19 | — | — | WO | disclosed |