Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EPOR | P19235 | 2/20 | 0.40 |
| ▸ | CPA3 | P15088 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19384899 | 0.85 | CPA3 (0.53) | NPC1RAB9AEPORCPA3CYP1A2 | |
| SCHEMBL536547 | 0.85 | CPA3 (0.53) | NPC1RAB9AEPORCPA3CYP1A2 | |
| SCHEMBL536546 | 0.85 | CPA3 (0.53) | NPC1RAB9AEPORCPA3CYP1A2 | |
| Hydrochloric Acid SCHEMBL3025758 | 0.84 | CPA3 (0.51) | NPC1RAB9AEPORCPA3CYP1A2 | |
| Hydrochloric Acid SCHEMBL3025760 | 0.84 | CPA3 (0.51) | NPC1RAB9AEPORCPA3CYP1A2 | |
| SCHEMBL8398528 | 0.83 | NPC1 (0.41) | NPC1RAB9AEPORCPA3KMT2A | |
| SCHEMBL840672 | 0.79 | LMNA (0.46) | L3MBTL1NPC1RAB9AEPORKMT2A | |
| SCHEMBL841385 | 0.79 | LMNA (0.46) | L3MBTL1NPC1RAB9AEPORKMT2A | |
| SCHEMBL842165 | 0.78 | GRIK1 (0.53) | TDP1NPC1RAB9AEPORKMT2A | |
| SCHEMBL22444192 | 0.78 | KMT2A (0.44) | NPC1RAB9AEPORKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150141615-A1 | ALDEHYDE ACETAL BASED PROCESSES FOR THE MANUFACTURE OF MACROCYCLIC DEPSIPEPTIDES AND NEW INTERMEDIATES | NOVARTIS AG (CH) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141615-A1 | ALDEHYDE ACETAL BASED PROCESSES FOR THE MANUFACTURE OF MACROCYCLIC DEPSIPEPTIDES AND NEW INTERMEDIATES | DNPEP, VIP, ALDH16A1 | TDP1 4092/4885L3MBTL1 2147/4885CES2 2186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.