Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16714180 | 1.00 | HTR2A (0.51) | HTR2AKCNH2HTR2CHTR6RELA | |
| SCHEMBL16714166 | 0.95 | HTR2A (0.48) | HTR2AKCNH2HTR2CHTR6RELA | |
| SCHEMBL16714165 | 0.95 | HTR2A (0.48) | HTR2AKCNH2HTR2CHTR6RELA | |
| SCHEMBL16181728 | 0.87 | HTR6 (0.59) | HTR6ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL18194391 | 0.87 | HTR6 (0.59) | HTR6ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL18194407 | 0.85 | HTR6 (0.54) | HTR2CHTR6ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL29335666 | 0.83 | HTR6 (0.56) | HTR6ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL275802 | 0.82 | RELA (0.60) | RELAALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL275803 | 0.82 | RELA (0.60) | RELAALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL14018370 | 0.82 | RELA (0.60) | RELAALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150137083-A1 | CONJUGATED AROMATIC DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE USING THE SAME | NATIONAL TSING HUA UNIVERSITY (TW) | 2015-05-21 | — | — | US | disclosed |