Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 13/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL16714347 | 1.00 | CFD (0.40) | CFDMAOBMAOAKDM1ACTSC | |
| SCHEMBL15541899 | 0.94 | MAOB (0.41) | CFDMAOBMAOAKDM1A | |
| Trifluoroacetic Acid SCHEMBL16714405 | 0.76 | SMN1; SMN2 (0.47) | KDM1A | |
| SCHEMBL15540514 | 0.74 | MAOB (0.49) | CFDMAOBMAOAKDM1A | |
| SCHEMBL15542080 | 0.74 | MAOB (0.49) | CFDMAOBMAOAKDM1A | |
| SCHEMBL19592182 | 0.73 | MAOB (0.44) | CFDMAOBMAOAKDM1A | |
| Trifluoroacetic Acid SCHEMBL16714355 | 0.72 | CFD (0.38) | CFDCTSC | |
| SCHEMBL6425159 | 0.70 | MAOB (0.54) | CFDMAOBMAOAKDM1A | |
| SCHEMBL6425162 | 0.70 | MAOB (0.54) | CFDMAOBMAOAKDM1A | |
| Trifluoroacetic Acid SCHEMBL15541143 | 0.70 | PDK1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815819-B2 | Complement pathway modulators and uses thereof | NOVARTIS AG (CH) | 2017-11-14 | — | — | US | disclosed |
| US-20150141455-A1 | COMPLEMENT PATHWAY MODULATORS AND USES THEREOF | NOVARTIS AG (CH) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141455-A1 | COMPLEMENT PATHWAY MODULATORS AND USES THEREOF | C5, C3AR1, C9 | CFD 9/4885MAOB 265/4885MAOA 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.