Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | RAB9A | P51151 | 1/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.82 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.72 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.72 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.67 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.67 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.67 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.67 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.67 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.67 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.67 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.67 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.67 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.67 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.67 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.67 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.67 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16714818 | 1.00 | NPC1 (0.82) | NPC1LMNARAB9ASMN1; SMN2SOAT2 | |
| SCHEMBL7203505 | 0.91 | RAB9A (1.00) | NPC1LMNARAB9ASMN1; SMN2SOAT2 | |
| SCHEMBL11418581 | 0.90 | NPC1 (0.66) | NPC1LMNARAB9ASMN1; SMN2SOAT2 | |
| SCHEMBL11418584 | 0.90 | NPC1 (0.66) | NPC1LMNARAB9ASMN1; SMN2SOAT2 | |
| SCHEMBL28931481 | 0.87 | RAB9A (0.91) | NPC1LMNARAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL29379899 | 0.84 | SOAT2 (1.00) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| Oleic Acid Anilide SCHEMBL4143904 | 0.84 | SOAT2 (1.00) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| Oleic Acid Anilide SCHEMBL4143902 | 0.84 | SOAT2 (1.00) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL28882029 | 0.84 | RAB9A (0.81) | NPC1LMNARAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL9310867 | 0.82 | SOAT2 (0.67) | NPC1LMNARAB9ASMN1; SMN2SOAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150140588-A1 | Lipase Variants and Polynucleotides Encoding Same | NOVOZYMES A/S (DK) | 2015-05-21 | — | — | US | disclosed |
| CN-103827298-A | Lipase variants and polynucleotides encoding same | NOVOZYMES AS | 2014-05-28 | — | — | CN | disclosed |