SCHEMBL16714846

SCHEMBL16714846

CO[SiH](CCC(C)N(C)C)OC

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 12/20 0.36
CHRNA4 P43681 12/20 0.36
CHRNB4 P30926 9/20 0.36
CHRNA3 P32297 7/20 0.36
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16714738 0.77 CHRNB2 (0.35) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL16714845 0.77
SCHEMBL16714857 0.74 BCHE (0.30)
SCHEMBL409149 0.74
Ammonia Solution, Strong SCHEMBL28681250 0.72
SCHEMBL10390598 0.72
SCHEMBL16714789 0.71
SCHEMBL5420128 0.71
SCHEMBL14964182 0.70 OPRM1 (0.35)
SCHEMBL9722108 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9862812-B2 Composition containing nitrogen-containing organoxysilane compound and method for making the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
EP-2876111-B1 Composition containing nitrogen-containing organoxysilane compound and method for making the same SHINETSU CHEMICAL CO (JP) 2017-09-20 EP disclosed
EP-2876111-A1 Composition containing nitrogen-containing organoxysilane compound and method for making the same Shin-Etsu Chemical Co., Ltd. (JP) 2015-05-27 EP disclosed
US-20150135996-A1 COMPOSITION CONTAINING NITROGEN-CONTAINING ORGANOXYSILANE COMPOUND AND METHOD FOR MAKING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-21 US disclosed