SCHEMBL16714867

SCHEMBL16714867

CCO[Si](CC(C)NCc1ccccc1)(OCC)OCC

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.54
BCHE P06276 1/20 0.43
POLB P06746 3/20 0.41
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GAA P10253 1/20 0.40
ATM Q13315 1/20 0.40
CASR P41180 1/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAPK1 P28482 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16714856 0.86 SIGMAR1 (0.53) SIGMAR1BCHEPOLBMEN1KMT2A
SCHEMBL16714824 0.86 SIGMAR1 (0.53) SIGMAR1BCHEPOLBMEN1KMT2A
SCHEMBL16714786 0.83 SIGMAR1 (0.58) SIGMAR1BCHEPOLBMEN1KMT2A
SCHEMBL5810202 0.80 SIGMAR1 (0.40) SIGMAR1BCHEPOLBMEN1KMT2A
SCHEMBL16054556 0.77 MAPT (0.38) SIGMAR1L3MBTL1
SCHEMBL27245488 0.77 ALDH1A1 (0.45) SIGMAR1L3MBTL1GAAATMLMNA
SCHEMBL16714805 0.75 SIGMAR1 (0.56) SIGMAR1BCHEPOLBMEN1KMT2A
SCHEMBL16714808 0.75 SIGMAR1 (0.56) SIGMAR1BCHEPOLBMEN1KMT2A
SCHEMBL172633 0.75 SIGMAR1 (0.70) SIGMAR1BCHEPOLBLMNASMN1; SMN2
SCHEMBL13675825 0.75 SIGMAR1 (0.70) SIGMAR1BCHEPOLBLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9862812-B2 Composition containing nitrogen-containing organoxysilane compound and method for making the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
EP-2876111-B1 Composition containing nitrogen-containing organoxysilane compound and method for making the same SHINETSU CHEMICAL CO (JP) 2017-09-20 EP disclosed
EP-2876111-A1 Composition containing nitrogen-containing organoxysilane compound and method for making the same Shin-Etsu Chemical Co., Ltd. (JP) 2015-05-27 EP disclosed
US-20150135996-A1 COMPOSITION CONTAINING NITROGEN-CONTAINING ORGANOXYSILANE COMPOUND AND METHOD FOR MAKING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-21 US disclosed