Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.37 |
| ▸ | DNA2 | P51530 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30470782 | 0.86 | ALDH1A1 (0.40) | POLBALDH1A1LMNAMAPK1HTT | |
| SCHEMBL28007091 | 0.86 | ALDH1A1 (0.40) | POLBALDH1A1LMNAMAPK1HTT | |
| SCHEMBL12341859 | 0.80 | ALDH1A1 (0.49) | TSHRALDH1A1LMNAMAPK1HTT | |
| SCHEMBL2485439 | 0.80 | DTYMK (0.45) | DTYMKTSHRPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL1245686 | 0.79 | TSHR (0.57) | DTYMKTSHRPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL15371478 | 0.79 | TSHR (0.45) | DTYMKTSHRPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL15758062 | 0.78 | HCAR2 (0.46) | TSHRPOLBL3MBTL1ALDH1A1LMNA | |
| SCHEMBL4351783 | 0.75 | ALDH1A1 (0.49) | TSHRALDH1A1LMNAMAPK1HTT | |
| SCHEMBL6221966 | 0.74 | DTYMK (0.50) | DTYMKTSHRPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL2896179 | 0.74 | DTYMK (0.46) | DTYMKTSHRALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102321081-B | Preparation method of substituted enaminocarbonyl compound used as insecticide and intermediate | BAYER CROPSCIENCE AG | 2015-05-20 | — | — | CN | disclosed |
| CN-104507473-A | Antiviral drug for treatment of arenavirus infection | SIGA TECHNOLOGIES INC | 2015-04-08 | — | — | CN | disclosed |
| US-20110263556-A1 | New Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-27 | — | — | US | disclosed |
| WO-2011048004-A1 | INHIBITORS OF THE MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263556-A1 | New Compounds | PTGES, PTGER1, PTGS1 | DTYMK 4537/4885TSHR 2468/4885POLB 2618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.