Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694249 | 0.90 | KMT2A (0.60) | KMT2AMEN1ALDH1A1MAPTALOX12 | |
| SCHEMBL693838 | 0.82 | ATM (0.61) | KMT2AMEN1ALDH1A1MAPTALOX12 | |
| SCHEMBL2821027 | 0.79 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL694134 | 0.79 | ALDH1A1 (0.65) | KMT2AMEN1ALDH1A1MAPTALOX12 | |
| SCHEMBL693480 | 0.76 | OPRM1 (0.49) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL694495 | 0.75 | OPRM1 (0.51) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL3108469 | 0.73 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL15197206 | 0.73 | OPRM1 (0.47) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL15197199 | 0.72 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL728741 | 0.72 | KMT2A (0.48) | KMT2AMEN1ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2502921-B1 | Arylsulfonamide CCR3 antagonists | AXIKIN PHARMACEUTICALS INC (US) | 2015-05-20 | — | — | EP | disclosed |