Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720608 | 0.88 | HCAR1 (0.33) | KDM4EHCAR1 | |
| SCHEMBL16720380 | 0.82 | MAPT (0.31) | — | |
| SCHEMBL144228 | 0.81 | KCNH2 (0.33) | — | |
| SCHEMBL693686 | 0.81 | KCNH2 (0.33) | — | |
| SCHEMBL16720379 | 0.81 | IDO1 (0.40) | MEN1KMT2AGAAKDM4EBIRC5 | |
| SCHEMBL16720395 | 0.81 | ALDH1A1 (0.38) | MGLLMEN1KMT2AKDM4EHCAR1 | |
| SCHEMBL16720491 | 0.81 | DOT1L (0.39) | TDP1MGLLMEN1KMT2AHCAR1 | |
| SCHEMBL146857 | 0.80 | MAPT (0.41) | TDP1MEN1KMT2AKDM4EHCAR1 | |
| SCHEMBL5661417 | 0.79 | BIRC5 (0.47) | PTGS1PTGS2RAB9ATDP1MGLL | |
| SCHEMBL31310579 | 0.79 | BIRC5 (0.47) | PTGS1PTGS2RAB9ATDP1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |