Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719700 | 0.89 | FYN (0.44) | FYNKMT2AEGLN2APPGRIN1 | |
| SCHEMBL16719938 | 0.83 | KMT2A (0.64) | KMT2AAPPALDH1A1CYP19A1 | |
| SCHEMBL16720553 | 0.83 | KMT2A (0.44) | FYNKMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16719562 | 0.75 | KMT2A (0.44) | FYNKMT2AAPPCYP19A1 | |
| SCHEMBL22022092 | 0.73 | ACLY (0.54) | FYNKMT2AACLYCYP19A1 | |
| SCHEMBL18230486 | 0.73 | HTR2A (0.30) | — | |
| SCHEMBL22003808 | 0.72 | ACLY (0.49) | FYNKMT2AALDH1A1ACLYCYP19A1 | |
| SCHEMBL16720916 | 0.72 | BRAF (0.38) | KMT2A | |
| SCHEMBL16720520 | 0.71 | KMT2A (0.44) | FYNKMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16719747 | 0.71 | KMT2A (0.64) | KMT2AAPPALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |