Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.38 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720186 | 0.74 | TYR (0.47) | MEN1POLBMAPK1KMT2ATYR | |
| SCHEMBL16719814 | 0.74 | TYR (0.47) | MEN1POLBMAPK1KMT2ATYR | |
| SCHEMBL16719527 | 0.74 | MEN1 (0.44) | MEN1POLBMAPK1KMT2ATYR | |
| SCHEMBL16719421 | 0.74 | MAPK1 (0.51) | MEN1POLBMAPK1KMT2AL3MBTL1 | |
| SCHEMBL30620465 | 0.74 | MEN1 (0.73) | MEN1POLBMAPK1KMT2AL3MBTL1 | |
| SCHEMBL1224829 | 0.74 | MEN1 (0.73) | MEN1POLBMAPK1KMT2AL3MBTL1 | |
| SCHEMBL16720494 | 0.73 | TYR (0.46) | MEN1POLBMAPK1KMT2ATYR | |
| SCHEMBL16720488 | 0.73 | ABL1 (0.41) | MAPK1ESR1MAOAABL1ABCB1 | |
| SCHEMBL30620464 | 0.72 | MEN1 (0.66) | MEN1POLBMAPK1KMT2ATYR | |
| SCHEMBL16720142 | 0.72 | BACE1 (0.46) | MEN1POLBMAPK1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |