Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 3/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719814 | 0.83 | TYR (0.47) | TYRAHRFFAR4APPENPP2 | |
| SCHEMBL16720143 | 0.74 | MEN1 (0.51) | TYRAHRAPPENPP2ESR1 | |
| SCHEMBL16720591 | 0.71 | TYR (0.47) | TYRAHRAPPENPP2CMA1 | |
| SCHEMBL16720188 | 0.71 | AHR (0.44) | TYRAHRGPR84FFAR4HSD17B1 | |
| SCHEMBL1225643 | 0.71 | TYR (0.70) | TYRAHRENPP2CMA1USP2 | |
| SCHEMBL16720494 | 0.71 | TYR (0.46) | TYRAHRENPP2CMA1USP2 | |
| SCHEMBL16720508 | 0.70 | HSD17B1 (0.47) | HSD17B1HSD17B2ESR1ESR2ALDH1A1 | |
| Bromide SCHEMBL27298210 | 0.70 | TYR (0.68) | TYRAHRFFAR4ENPP2CMA1 | |
| SCHEMBL16720654 | 0.70 | ESR1 (0.37) | HSD17B1HSD17B2ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL27297304 | 0.70 | TYR (0.68) | TYRAHRENPP2CMA1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |