Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719816 | 0.80 | AHR (0.44) | MEN1KMT2APOLBMAPK1APP | |
| SCHEMBL16720188 | 0.80 | AHR (0.44) | MEN1KMT2APOLBMAPK1APP | |
| SCHEMBL731067 | 0.79 | PRKCQ (0.52) | MEN1KMT2ABRD4TLR8TLR7 | |
| SCHEMBL16720400 | 0.76 | MEN1 (0.46) | MEN1KMT2APOLBMAPK1BRD4 | |
| SCHEMBL18392225 | 0.72 | PDE4C (0.52) | MEN1KMT2APOLBMAPK1BRD4 | |
| SCHEMBL16720490 | 0.72 | KDM1A (0.43) | MAPK1MAPTCNR2 | |
| SCHEMBL16720143 | 0.71 | MEN1 (0.51) | MEN1KMT2APOLBMAPK1APP | |
| SCHEMBL16719527 | 0.71 | MEN1 (0.44) | MEN1KMT2APOLBMAPK1APP | |
| SCHEMBL16720495 | 0.71 | TYR (0.46) | MEN1KMT2APOLBMAPK1BRD4 | |
| SCHEMBL16720145 | 0.70 | PDE4B (0.46) | MAPK1MAPTPDE4CCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |