Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 4/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720407 | 0.85 | AHR (0.47) | NPC1AHRCYP2A6TRPA1CA1 | |
| SCHEMBL27417145 | 0.84 | CYP2A6 (0.43) | NPC1AHRNR4A2CYP2A6F7 | |
| SCHEMBL8404071 | 0.79 | GABRP (0.48) | NPC1AHRNR4A2CYP2A6F7 | |
| SCHEMBL9091484 | 0.78 | CYP19A1 (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL803139 | 0.74 | KMT2A (0.50) | NPC1USP2CA1CA2MAPT | |
| SCHEMBL26259748 | 0.74 | MAPT (0.50) | NPC1GAANPSR1MAPTCYP1A2 | |
| SCHEMBL26259867 | 0.72 | CYP19A1 (0.48) | NPC1GAANPSR1MAPTCYP1A2 | |
| SCHEMBL3340549 | 0.72 | LTA4H (0.48) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL1122665 | 0.72 | GABRP (0.48) | NPC1AHRNR4A2CYP2A6F7 | |
| SCHEMBL25203062 | 0.72 | GABRP (0.45) | NPC1AHRNR4A2CYP2A6F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |