Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719776 | 0.82 | ALDH1A1 (0.37) | ALDH1A1HDAC1 | |
| SCHEMBL16719468 | 0.82 | KDM5A (0.32) | ALDH1A1 | |
| SCHEMBL16720262 | 0.80 | KDM5A (0.45) | HDAC1HDAC2 | |
| SCHEMBL16719585 | 0.80 | KDM5A (0.31) | — | |
| SCHEMBL16720282 | 0.77 | KDM5A (0.33) | ALDH1A1LMNA | |
| SCHEMBL16719854 | 0.77 | ABL1 (0.34) | ALDH1A1 | |
| SCHEMBL5941013 | 0.75 | ALDH1A1 (0.48) | ALDH1A1LMNAHDAC1HDAC2 | |
| SCHEMBL16719637 | 0.75 | ESR1 (0.42) | ALDH1A1LMNA | |
| SCHEMBL16720023 | 0.74 | ACLY (0.39) | ALDH1A1 | |
| SCHEMBL9988102 | 0.72 | BACE1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |