Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23432750 | 0.77 | DRD2 (0.43) | MAPK1ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL23432749 | 0.77 | DRD2 (0.43) | MAPK1ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL13462411 | 0.76 | S1PR1 (0.37) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL256749 | 0.76 | NOTUM (0.56) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL23055638 | 0.76 | DRD3 (0.56) | MAPK1MAPTKDM4EADRA2ACYP2D6 | |
| SCHEMBL25044260 | 0.74 | KDM4E (0.35) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL2484100 | 0.74 | ADRA2C (0.44) | MAPK1ALDH1A1MAPTCYP1A2KDM4E | |
| SCHEMBL2625772 | 0.74 | NOTUM (0.57) | ADRA2ACYP2D6ADRA2BADRA2CADRA1D | |
| SCHEMBL2625776 | 0.74 | NOTUM (0.57) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL94532 | 0.74 | DRD2 (0.46) | NOTUMDRD2DRD3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |